A yolk sac tumor (YST) is a rare cancer that mainly affects young kids, especially boys before puberty. It starts from germ cells, which are supposed to turn into eggs or sperm but end up growing uncontrollably instead. YST usually shows up as a lump in the testes for boys, or in the ovaries for girls.
Sometimes, it can even develop in the chest causing a space between the lungs. However, the exact cause isn’t fully known, but it might be due to abnormal cell growth, genetic factors, or developmental issues. In this article we’re going to be looking at treatment options and prognosis.

Diagnostic procedures
For the diagnosis process of yolk sac tumor the doctor takes a small piece of the tumor and checks it under a microscope to see if this cancer. Then the doctor uses an international germ cell cancer consensus classification to see how serious the cancer is. With this classification the doctor can see how far the cancer has spread and then decide a treatment to use for the tumor.
Treatment of Yolk Sac Tumor
Surgical Resection: The first and obvious treatment option is to remove the tumor from the original site. This is really necessary to get rid of the cancer.
Chemotherapy Regimens: After surgery, the cancerous cells might still linger in the original site. Because of that possibility, patients undergo chemotherapy to kill any leftover cancerous cells.
There are two common regimens for this treatment option. The first is BEP which is a combination of bleomycin, etoposide, and cisplatin. The second combination is VIP, which is made up of etoposide, ifosfamide, and cisplatin.
Radiation Therapy: If surgery isn’t an option or in a case where cancerous cells still linger even after chemo, radiation therapy. Radiation is used to target and kill the remaining cancer cells.
Follow-up: It doesn’t just end at radiation therapy. While that treatment option is effective, there’s still a chance of the tumor forming after a while. Because of that, it is advised that the patient go in for regular checkups.
Prognosis of Yolk Sac
The prognosis for yolk sac tumors is generally positive, most especially if the tumor is caught early and then treated. Many kids with yolk sac tumors have a good chance of recovery, because of advanced technology like radiation therapy.
Prognosis can be affected by how far the tumor has spread before it is diagnosed. Secondly, where the tumor is located can affect how easy it is to treat.
Summary
A yolk sac tumor (YST) is a rare cancer that mainly affects young boys, but can also occur in girls. It begins in germ cells and typically appears as a lump in the testes, ovaries, or chest. Doctors diagnosed the yolk sac tumor using a biopsy and classification methods.
Treatment for a yolk sac tumor usually starts with surgery, followed by chemotherapy and possibly radiation.
However , regular follow-ups are important to monitor for recurrence of the tumor.