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Yolk Sac Tumor: Origin, Development, Symptoms, and Causes

Christabel EgbeamabyChristabel Egbeama
September 5, 2024
in Health
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Yolk Sac Tumor: Origin, Development, Symptoms, and Causes
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A yolk sac tumor (YST) is a rare type of cancer affecting young kids. Yolk sac tumors account for approximately 3.5% of all childhood cancers in those under 15 years of age, with the highest incidence in prepubertal boys, where they represent about 30% of testicular germ cell tumors. YST being a type of germ cell tumor means it comes from the cells that are supposed to develop into eggs or sperm.

Photo by derneuemann

Table of Contents

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  • Origin and Development
  • Symptoms of Yolk Sac Tumor
  • Causes of Yolk Sac Tumor
  • Conclusion

Origin and Development

Typically, yolk sac tumors start from germ cells, these cells are early cells that later become eggs or sperm. In a normal development process, these cells move to the gonads (testes or ovaries), which grow into mature reproductive cells.

However, in the case of yolk sac tumors these cells grow uncontrollable, eventually leading to cancer. These tumors usually make a substance called alpha-fetoprotein (AFP) which serves as a diagnose helper to track the tumor.

In males, the yolk sac tumors typically show you in the testes. They might come in the form of a lump in the scrotum, which could sometimes be a mix with other types of testicular tumors.

In females, these tumors are usually found in the ovaries. Just like the tumor makes the scrotum swell, it makes the female belly swell. Moreover, in rare cases, the yolk sac tumor can develop a space in the chest just between the lungs called the mediastinum.

Symptoms of Yolk Sac Tumor

  • A lump or swelling in the testes or ovaries
  • Abdominal pain or swelling
  • Trouble breathing or chest pain (if the tumor is in the chest area)
  • Fatigue or feeling unusually tired.
  • Fever without any clear reason
  • Nausea or vomiting (especially if the tumor is large)
  • Weight loss without trying
  • Early puberty signs in young children (in rare cases)

Causes of Yolk Sac Tumor

There’s not a clear cause of yolk sac tumor formation. However, it has something to do with how certain cells grow. Here are a few things that could cause a yolk sac tumor to form:

Abnormal Germ Cell Development: The tumor comes from germ cells which are supposed to turn into eggs or sperm. Sometimes these cells don’t develop properly due to genetic mutation or even exposure to harmful substances. These abnormally grown cells then begin to turn into tumors.

Genetic Factors: This one is pretty straightforward. There might be something in your genes that increases the risk of developing a yolk sac tumor. This can be attributed to a family member having a similar type of tumor, which makes the risk higher.

Developmental Issues: If there are problems with how your reproductive organs develop, like in boys with undescended testes, it might make it more likely for a yolk sac tumor to form. These issues can create conditions where germ cells don’t grow the way they should.

Spontaneous Occurrence: Sometimes, yolk sac tumors just happen out of the blue, with no obvious cause or risk factors. Even without any clear reason, a child or young adult could end up with this type of tumor.

Conclusion

If you notice a lump in the testes or ovaries, or if you have ongoing belly pain, you should see a doctor. Also, if you’re having trouble breathing, chest pain, or extreme tiredness, get it checked out. Unexplained fevers, frequent nausea or vomiting, sudden weight loss, or early puberty signs in kids are also important to discuss with a doctor.

Tags: and Causesdevelopmentfederal characterhealthsymptomsYolk Sac Tumor: Origin
Christabel Egbeama

Christabel Egbeama

Christabel Egbeama is a health writer and aspiring consultant engineer who recently completed her bachelor's degree in civil engineering. Her passion for safety in the construction industry led her to delve into public health writing. Having undergone training in health, safety, and environment, Christabel has established a foundation rich in comprehending the broader spectrum of health and its benefits for individuals across various ages and professions. She now produces compelling holistic health articles aimed at guiding individuals towards informed decisions for a healthier tomorrow, encouraging lifestyle modifications.

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